UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                    FORM 8-K

                                 CURRENT REPORT

                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934

                Date of Report (Date of earliest event reported)
                                 July 22, 2009

                           HEMISPHERX BIOPHARMA, INC.
             (Exact name of registrant as specified in its charter)

                           Delaware 0-27072 52-0845822
         (state or other jurisdiction (Commission File (I.R.S. Employer
                  of incorporation) Number) Identification No.)

              1617 JFK Boulevard, Philadelphia, Pennsylvania 19103
               (Address of principal executive offices) (Zip Code)

       Registrant's telephone number, including area code: (215) 988-0080


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                 (former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_| Written communications pursuant to Rule 425 under the Securities Act (17 CFR
230.425)

|_| Soliciting material pursuant to Rule 14a-12 under the Securities Act (17 CFR
230.14a-12)

|_| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange
Act (17 CFR 240-14d-2(b))

|_| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange
Act (17CFR 240-13e-4(c))






Item 8.01 Other Events


Hemispherx Biopharma Announces Further Adjournment on Proposal Number 3 from the
2009 Annual Meeting of Stockholders

For more information, please see the July 22,2009 press release filed as exhibit
99.1 to this report.


Item 9.01 Financial Statements and Exhibits.

(d)    Exhibits

The following Exhibit is filed as part of this report:

Exhibit No.    Description
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Exhibit 99.1 Press Release dated July 22, 2009.


                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.

                                          HEMISPHERX BIOPHARMA, INC.

July 22, 2009                        By:  /s/ William A. Carter
                                          -------------------------------------
                                          William A. Carter, M.D.
                                          Chief Executive Officer





                                                                    Exhibit 99.1







Company/Investor Contact:
Dianne Will
Hemispherx Biopharma, Inc.
518-398-6222
ir@hemispherx.net

     Hemispherx Biopharma Announces Further Adjournment on Proposal Number 3
                  from the 2009 Annual Meeting of Stockholders

PHILADELPHIA, PA--July 22, 2009--Hemispherx Biopharma (NYSE AMEX: HEB) announced
today that the Company will extend the time allowed for  stockholders to vote on
proposal  number 3  contained  in the  proxy  for the  2009  Annual  Meeting  of
Stockholders  in order to permit  stockholders  additional  time.  The adjourned
meeting  will  be held at the  Embassy  Suites  Hotel,  1776  Benjamin  Franklin
Parkway,  Philadelphia,  Pennsylvania  19103,  on Friday,  September 4, 2009, at
10:00 a.m. Eastern time. The record date remains May 8, 2009.

As previously  announced,  the 2009 Annual Meeting of  Stockholders  was held as
scheduled on June 24, 2009 on three of the four proposals.  The Company left the
polls open with regard to voting on proposal 3, an amendment of its  certificate
of  incorporation  to increase the number of  authorized  shares of Common Stock
from  200,000,000 to 350,000,000 and adjourned the meeting solely with regard to
this  proposal.  The  Company  did  this  due to the low  vote  turn out and the
requirement  that this  proposal be approved by the holders of a majority of the
outstanding shares. Less than the requisite number of shares for approval of the
proposal were present at the meeting.

The Company  believes that the low turnout may be due to the fact that more than
40% of its  outstanding  shares are held outside the United States and that many
of these shares are held at European banks that do not  necessarily  participate
in the voting of proxies of American companies. In addition, the voting has been
impacted by stockholders that may be on summer holiday.

Hemispherx  urges all  stockholders who owned shares on May 8, 2009 and have not
already voted to do so  immediately.  Stockholders  who have already voted,  but
would like to change their vote, may do so by casting another ballot.  Please be
advised that this applies to proposal  number 3 only as the polls have closed on
proposals 1, 2 and 4. United  States  stockholders  will  receive an  additional
proxy card electronically or in the mail.

As noted above, a significant number of stockholders are domiciled in Europe and
less  readily  accessible  for  notification  purposes.  European  banks  do not
necessarily  forward the proxy to European  stockholders,  and  therefore  these
stockholders will need to contact their bank directly in order to exercise their
right to vote.

A replacement proxy card and letter to stockholders will be sent out shortly via
e mail or regular mail,  depending on how  stockholders  have elected to receive
this material. The annual report and proxy statement will not be re-mailed.  For
notice and access purposes, the Company has posted a copy of the proxy statement
and      annual      report      on      the      Company's      website      at
http://www.hemispherx.net/content/investor/annualMeeting.asp.  For the  non-U.S.
residents, the Company has also posted a blank proxy card, which they may use to
instruct  their  bank to vote on their  behalf.  Some  European  banks will vote
directly on behalf of the  stockholder as  instructed.  Other banks will issue a
legal  proxy or  certificate  certifying  the  number of shares  owned as of the
record  date (May 8,  2009),  which  must be  accompanied  by a signed and dated
proxy. These shares do not need to be blocked.  The banks simply need to certify
the number of shares owned on May 8, 2009. If needed,  please  forward a copy of
the sample certificate posted on the website to your European bank.

The Company  emphasizes the importance of your vote. If you are a U.S. resident,
please take a moment to vote your shares via Internet,  phone,  or by mail.  All
other stockholders are encouraged to contact your custodian  bank/broker at your
earliest convenience.

If you need  assistance  in voting your  shares,  Hemispherx  suggests  that you
contact  Morrow & Co.,  LLC,  the firm  assisting  the  Company  with the Annual
Meeting.  Morrow & Co. can be contacted in the U.S. at 203-658-9400 or in London
at  +44-207-222-4645.  Stockholders  may  also  contact  Dianne  Will,  Investor
Relations   for   Hemispherx   collect  at   518-398-6222   or  via  e  mail  at
dwill@willstar.net.

About Hemispherx Biopharma

Hemispherx  Biopharma,  Inc.  is a  specialty  pharma  company  engaged  in  the
manufacture  and clinical  development  of new drug  entities  for  treatment of
seriously debilitating disorders. Hemispherx's flagship products include Alferon
N Injection(R)  (FDA approved for a category of sexually  transmitted  diseases)
and the  experimental  therapeutics,  Ampligen(R)  and Oragens.  Ampligen(R) and
Oragens  represent  experimental  RNA nucleic acids being developed for globally
important debilitating diseases and disorders of the immune system. Hemispherx's
platform  technology  includes  large and small agent  components  for potential
treatment  of  various  severely  debilitating  and life  threatening  diseases.
Hemispherx has in excess of 50 issued patents  comprising its core  intellectual
property estate and a fully commercialized product (Alferon N Injection(R)). The
Company  wholly  owns and  exclusively  operates a GMP  certified  manufacturing
facility in the United  States for  commercial  products.  For more  information
please visit www.hemispherx.net.

Information  contained in this news release other than  historical  information,
should be considered  forward-looking and is subject to various risk factors and
uncertainties. For instance, the strategies and operations of Hemispherx involve
risk of competition,  changing market conditions, change in laws and regulations
affecting these industries and numerous other factors  discussed in this release
and in the Company's  filings with the Securities and Exchange  Commission.  Any
specifically referenced investigational drugs and associated technologies of the
Company  (including  Ampligen(R),  Alferon LDO and Oragens) are  experimental in
nature  and as such  are not  designated  safe  and  effective  by a  regulatory
authority for general use and are legally available only through clinical trials
with the referenced  disorders.  The  forward-looking  statements  represent the
Company's  judgment  as of the  date of this  release.  The  Company  disclaims,
however,  any intent or obligation to update these  forward-looking  statements.
Clinical trials for other potential indications of the approved biologic Alferon
N Injection(R) do not imply that the product will ever be specifically  approved
commercially for these other treatment indications; similarly, the completion of
the NDA filing  process  with  Ampligen(R)  does not imply that the product will
ever be approved commercially.