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                                  UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                        --------------------------------

                                    FORM 8-K
                        --------------------------------


                                 CURRENT REPORT
                     PURSUANT TO SECTION 13 OR 15(D) OF THE
                         SECURITIES EXCHANGE ACT OF 1934

      DATE OF REPORT (DATE OF EARLIEST EVENT REPORTED): SEPTEMBER 30, 2005

                             -----------------------

                                 CRYOLIFE, INC.
             (Exact name of registrant as specified in its charter)
                            -------------------------


                                                                                   
                FLORIDA                                 1-13165                              59-2417093
     (State or Other Jurisdiction              (Commission File Number)                     (IRS Employer
           of Incorporation)                                                             Identification No.)


              1655 ROBERTS BOULEVARD, N.W., KENNESAW, GEORGIA 30144
               (Address of principal executive office) (zip code)

       REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE: (770) 419-3355

          -------------------------------------------------------------
          (Former name or former address, if changed since last report)

                            -------------------------

     Check the  appropriate  box below if the Form 8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2. below):

|_|  Written  communications  pursuant to Rule 425 under the  Securities Act (17
     CFR 230.425)

|_|  Soliciting  material pursuant to Rule 14a-12 under the Exchange Act (17 CFR
     240.14a-12)

|_|  Pre-commencement   communications  pursuant  to  Rule  14d-2(b)  under  the
     Exchange Act (17 CFR 240.14d-2(b))

|_|  Pre-commencement   communications  pursuant  to  Rule  13e-4(c)  under  the
     Exchange Act (17 CFR 240.13e-4(c))

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SECTION 1.  REGISTRANT'S BUSINESS AND OPERATIONS

ITEM 1.01   ENTRY INTO A MATERIAL DEFINITIVE AGREEMENT

GERALD B. SEERY IS APPOINTED SENIOR VICE PRESIDENT OF SALES AND MARKETING.

     Cryolife,  Inc.  ("Cryolife")  has  appointed  Gerald B. Seery to the newly
created  position of Senior Vice  President  of Sales and  Marketing,  effective
October  1,  2005.  Mr.  Seery  joined  CryoLife  in 1993 and has  held  several
positions with the Company  including  Marketing  Manager for vascular  tissues,
Director of  Marketing,  Vice  President  of  Marketing,  and  President  of the
Aurazyme  subsidiary.  Mr. Seery had been President of CryoLife Europa, based in
the U.K.,  for three years  before his return to the United  States.  On July 1,
2005, Cryolife appointed him Vice President of International Operations.

     Mr.  Seery is a graduate of The Catholic  University  of America and has an
MBA from Columbia University. Mr. Seery reports to Steven G. Anderson, President
and CEO of CryoLife, Inc.

     Effective October 1, 2005, Mr. Seery receives a base salary of $250,000. In
addition,  he will  receive  a  percentage  of any net  increase  in  CryoLife's
revenues  during the last  quarter of 2005 as  compared  to the last  quarter of
2004.  Mr. Seery does not have a written  employment  agreement  with  Cryolife.
However, his employment requires a 30-day notice of termination.

THE COMPANY'S  COMPENSATION  COMMITTEE APPROVES  ACCELERATED  VESTING OF CERTAIN
OPTIONS.

     On September 30, 2005, CryoLife's Compensation Committee, composed entirely
of independent  directors,  approved the acceleration of vesting of unvested and
"out-of-the-money" options previously awarded to employees,  including executive
officers,  with  option  exercise  prices  greater  than $6.97  effective  as of
September 30, 2005. Options held by non-employee directors are fully vested. The
accelerated  vesting  covered options to acquire an aggregate of 166,925 shares,
at exercise prices ranging from $7.06 to $31.99.

Options held by the following individuals,  who were named in the Company's most
recent  proxy  statement  as  the  most  highly  paid  officers  in  2004,  were
accelerated as shown:



                                                                               
               Name                             Principal Position                   Number of Options Accelerated
               ----                             ------------------                   -----------------------------
Steven G. Anderson                  Chairman of the Board, President                              82,693
                                        and Chief Executive Officer

David Ashley Lee                    Executive Vice President, Chief                               10,822
                                        Operating Officer and Chief
                                        Financial Officer

Albert E. Heacox, Ph.D.             Senior Vice President, Research                                4,000
                                        and Development

David M. Fronk                      Vice President, Regulatory Affairs                             9,684
                                        and Quality Assurance



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The decision to accelerate  vesting of these  underwater  stock options was made
primarily to avoid recognizing  compensation cost in the Consolidated  Statement
of Operations in future  financial  statements upon the adoption of Statement of
Financial  Accounting  Standards No. 123 (revised 2004),  "Share-Based  Payment"
("SFAS 123R"),  which, when effective,  will require all share-based payments to
employees,  including  grants of employee  stock options to be recognized on the
Company's  financial  statements based on their fair values.  SFAS 123R has been
adopted by the Company beginning October 1, 2005.

SECTION 2   FINANCIAL INFORMATION.

ITEM 2.03.  CREATION OF A DIRECT FINANCIAL  OBLIGATION OR AN OBLIGATION UNDER AN
OFF- BALANCE SHEET ARRANGEMENT OF A REGISTRANT.

     On September  30, 2005,  the Company  borrowed  approximately  $3.5 million
under its credit agreement with Wells Fargo Foothill, Inc., to fund a portion of
its payment  obligations  under the  settlement of the  securities  class action
lawsuit.  The Company  described  the terms of the  settlement  in its Form 8-K,
dated and filed on July 28, 2005, which is incorporated herein by reference.

     The  Company  reported  the terms of the credit  agreement  in its Form 8-K
dated February 8, 2005 and filed on February 11, 2005.  The Company  reported an
amendment to the revolving  credit agreement on its Form 8-K dated September 27,
2005 and  filed on  September  28,  2005.  The  Company  incorporates  herein by
reference the information  set forth in Item 2.03 of these two Form 8-Ks.  Under
the credit agreement, the Company's interest rate on this borrowing is currently
7.75% per annum.



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                                   SIGNATURES

     Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,
CryoLife,  Inc.  has duly  caused  this report to be signed on its behalf by the
undersigned hereunto duly authorized.

                                       CRYOLIFE, INC.



Date:  October 3, 2005                 By:  /s/ D. A. Lee
                                          ------------------------------------
                                          Name:  D. Ashley Lee
                                          Title: Executive Vice President, Chief
                                                 Operating Officer and Chief
                                                 Financial Officer

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