SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549


                                    FORM 8-K


                                 CURRENT REPORT

                       Pursuant to Section 13 or 15(d) of
                       the Securities Exchange Act of 1934


         Date of Report                                              May 9, 2006
(Date of earliest event reported)                                    May 9, 2006

                               QCR Holdings, Inc.
             (Exact name of Registrant as specified in its charter)

                                    Delaware
                 (State or other jurisdiction of incorporation)

        0-22208                                        42-1397595
(Commission File Number)                 (I.R.S. Employer Identification Number)

3551 Seventh Street, Suite 204, Moline, Illinois                         61265
    (Address of principal executive offices)                          (Zip Code)

                          (309) 736-3580 (Registrant's
                     telephone number, including area code)

                                 Not Applicable
          (Former name or former address, if changed since last report)

Check  the  appropriate  box  below  if the  Form  8-K  filing  is  intended  to
simultaneously  satisfy the filing obligation of the registrant under any of the
following provisions (see General Instruction A.2 below):

     [      ]  Written   communications   pursuant  to  Rule  425  under  the
               Securities Act (17 CFR 230.425)

     [      ]  Soliciting  material pursuant to Rule 14a-12 under the Exchange
               Act (17 CFR 240.14a-12)

     [      ]  Pre-commencement communications pursuant to Rule 14d-2(b) under
               the Exchange Act (17 CFR 240.14d-2(b))

     [      ]  Pre-commencement communications pursuant to Rule 13e-4(c) under
               the Exchange Act (17 CFR 240.13e-4(c))


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Item 2.02.  Results of Operations and Financial Condition

On May 9, 2006, QCR Holdings,  Inc. issued a shareholder  letter  discussing the
Company's  financial  results for the first  quarter,  ended March 31, 2006. The
letter is attached hereto as Exhibit 99.1.


Item 9.01 Financial Statements and Exhibits

          (a)  Exhibits.

                  99.1 Shareholder  letter dated May 2006 to be presented in the
                  quarterly shareholder publication, "Investor Update".





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                                   SIGNATURES

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
Registrant  has duly  caused  this  report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.



                                          QCR HOLDINGS, INC.


Dated:  May 9, 2006                       By: /s/ Todd A. Gipple
                                              ---------------------------------
                                              Todd A. Gipple
                                              Executive Vice President
                                              and Chief Financial Officer


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