Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  TVM V LIFE SCIENCE VENTURES GMBH & CO KG
2. Date of Event Requiring Statement (Month/Day/Year)
06/18/2013
3. Issuer Name and Ticker or Trading Symbol
bluebird bio, Inc. [BLUE]
(Last)
(First)
(Middle)
C/O TVM CAPITAL GROUP, MAXIMILIANSTRASSE 35C
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

MUNICH, 2M 80539
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Series A-1 Convertible Preferred Stock   (1)   (1) Common Stock 325,255 $ (1) D (5)  
Series A-2 Convertible Preferred Stock   (1)   (1) Common Stock 624,021 $ (1) D (5)  
Series B Convertible Preferred Stock   (1)   (1) Common Stock 935,783 $ (1) D (5)  
Series C Convertible Preferred Stock   (1)   (1) Common Stock 210,589 $ (1) D (5)  
Series D Convertible Preferred Stock   (1)   (1) Common Stock 158,709 $ (1) D (5)  
Series A-1 Warrants   (2) 11/16/2015 Series A-1 Convertible Preferred Stock (3) 660,982 $ 12.55 D (5)  
Series A-1 Warrants   (2) 10/26/2016 Series A-1 Convertible Preferred Stock (3) 440,650 $ 12.55 D (5)  
Series A-1 Warrants   (2) 05/03/2017 Series A-1 Convertible Preferred Stock (3) 1,038,674 $ 12.55 D (5)  
Series A-1 Warrants   (2) 08/28/2018 Series A-1 Convertible Preferred Stock (3) 236,062 $ 12.55 D (5)  
Series A-1 Warrants   (2) 12/18/2018 Series A-1 Convertible Preferred Stock (3) 236,062 $ 12.55 D (5)  
Series A-1 Warrants   (2) 04/15/2019 Series A-1 Convertible Preferred Stock (3) 462,681 $ 12.55 D (5)  
Series B Warrants   (2) 04/15/2019 Series B Convertible Preferred Stock (4) 287,400 $ 6.19 D (5)  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
TVM V LIFE SCIENCE VENTURES GMBH & CO KG
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    
TVM Capital GmbH
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    
Polack Axel
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    
SCHUHSLER HELMUT
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    
Goll Alexandra
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    
Birner Hubert
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    
Fischer Stefan
C/O TVM CAPITAL GROUP
MAXIMILIANSTRASSE 35C
MUNICH, 2M 80539
    X    

Signatures

/s/Stefan Fischer, Attorney-in-Fact for TVM V Life Science Ventures GmbH & Co. KG 06/18/2013
**Signature of Reporting Person Date

/s/Stefan Fischer, Attorney-in-Fact for TVM Capital GmbH 06/18/2013
**Signature of Reporting Person Date

/s/Stefan Fischer, Attorney-in-Fact for Axel Polack 06/18/2013
**Signature of Reporting Person Date

/s/Stefan Fischer, Attorney-in-Fact for Helmut Schuehsler 06/18/2013
**Signature of Reporting Person Date

/s/Stefan Fischer, Attorney-in-Fact for Alexandra Goll 06/18/2013
**Signature of Reporting Person Date

/s/Stefan Fischer, Attorney-in-Fact for Hubert Birner 06/18/2013
**Signature of Reporting Person Date

/s/Stefan Fischer 06/18/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The shares are convertible into bluebird bio, Inc. ("bluebird") Common Stock for the amounts shown and will automatically convert upon the closing of the initial public offering of bluebird without payment of further consideration.
(2) This warrant is immediately exercisable.
(3) Upon the closing of the initial public offering of bluebird, this warrant to purchase shares of Series A-1 Convertible Preferred Stock will automatically convert on an 18.967-for-one basis into a warrant to purchase shares of Common Stock.
(4) Upon the closing of the initial public offering of bluebird, this warrant to purchase shares of Series B Convertible Preferred Stock will automatically convert on an 18.967-for-one basis into a warrant to purchase shares of Common Stock.
(5) The shares are held directly by TVM V Life Science Ventures GmbH & Co. KG ("TVM V"). TVM V's general partner, TVM Capital GmbH ("TVM"), and its authorized officers, Axel Polack ("Polack"), Helmut Schuehsler ("Schuehsler"), Alexandra Goll ("Goll"), Hubert Birner ("Birner") and Stefan Fischer ("Fischer") may be deemed to share voting and dispositive power over the shares held by TVM V. Each of TVM, Polack, Schuehsler, Goll, Birner and Fischer disclaims beneficial ownership of these shares except to the extent of their pecuniary interest therein, if any.

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