Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
Williams Anre D
  2. Issuer Name and Ticker or Trading Symbol
AMERICAN EXPRESS CO [AXP]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Pres. Global Merchant Services
(Last)
(First)
(Middle)
AMERICAN EXPRESS TOWER, 200 VESEY ST., 3 WORLD FINANCIAL CENTER
3. Date of Earliest Transaction (Month/Day/Year)
05/02/2012
(Street)

NEW YORK, NY 10285
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/02/2012   M   22,848 A $ 43.977 83,786 D  
Common Stock 05/02/2012   M   30,845 A $ 45.768 114,631 D  
Common Stock 05/02/2012   M   29,700 A $ 51.865 144,331 D  
Common Stock 05/02/2012   M   30,000 A $ 57.77 174,331 D  
Common Stock 05/02/2012   M   20,000 A $ 58.54 194,331 D  
Common Stock 05/02/2012   M   50,000 A $ 49.13 244,331 D  
Common Stock 05/02/2012   S(1)   174,974 D $ 61.1754 (2) 69,357 D  
Common Stock               9.08 (3) I by 401(k) Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (Right to Buy) $ 43.977 05/02/2012   M     22,848 01/26/2005(4) 01/26/2014 Common Stock 22,848 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 45.768 05/02/2012   M     30,845 01/24/2006(4) 01/24/2015 Common Stock 30,845 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 51.865 05/02/2012   M     29,700 01/23/2007(4) 01/23/2016 Common Stock 29,700 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 57.77 05/02/2012   M     30,000 01/25/2008(4) 01/25/2017 Common Stock 30,000 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 58.54 05/02/2012   M     20,000 07/31/2008(4) 07/31/2017 Common Stock 20,000 $ 0 0 D  
Employee Stock Option (Right to Buy) $ 49.13 05/02/2012   M     50,000 01/31/2009(4) 01/31/2018 Common Stock 50,000 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Williams Anre D
AMERICAN EXPRESS TOWER, 200 VESEY ST.
3 WORLD FINANCIAL CENTER
NEW YORK, NY 10285
      Pres. Global Merchant Services  

Signatures

 /s/ Michael G. Kuchs, attorney-in-fact   05/03/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The reported disposition represents the sale of shares to cover the cost of exercise and withholding tax obligations arising from the stock options exercises reported above and the sale of 50% of the net shares acquired from these exercises; Mr. Williams will retain the balance of the net shares in accordance with the Company's retention guidelines for executive officers.
(2) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $61.01 to $61.29. The reporting person undertakes to provide to American Express Company, any security holder of American Express Company, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within this range.
(3) Shares held in reporting person's account under the Company's Retirement Savings Plan. This plan uses unit accounting, and the number of shares that a participant is deemed to hold varies with the unit price of the Company pooled stock fund.
(4) These options became exercisable in four equal annual installments beginning on date shown as "Date Exercisable."

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.