UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A (Amendment No. 2) UNDER THE SECURITIES EXCHANGE ACT OF 1934 VIOQUEST PHARMACEUTICALS, INC. ------------------------------ Common Stock, par value $0.001 per share (Title of Class of Securities) 927625103 CUSIP Number December 31, 2005 ----------------- (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is filed: | | Rule 13d-1(b) |X| Rule 13d-1(c) | | Rule 13d-1(d) *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). Continued on following pages Page 1 of 5 Pages SCHEDULE 13G (AMENDMENT NO. 1) CUSIP No. 927625103 Page 2 of 5 1 Names of Reporting Persons I.R.S. Identification Nos. of above persons (entities only) LINDSAY A. ROSENWALD, M.D. 2 Check the Appropriate Box If a Member of a Group * a. | | b. | | 3 SEC Use Only 4 Citizenship or Place of Organization UNITED STATES 5 Sole Voting Power Number of 3,425,999 Shares Beneficially 6 Shared Voting Power Owned By -0- Each Reporting 7 Sole Dispositive Power Person 3,425,999 With 8 Shared Dispositive Power -0- 9 Aggregate Amount Beneficially Owned by Each Reporting Person 3,425,999 10 Check Box If the Aggregate Amount in Row (9) Excludes Certain Shares * | | 11 Percent of Class Represented By Amount in Row (9) 7.2% 12 Type of Reporting Person * IN * see instructions before filling out CUSIP No. 927625103 PAGE 3 OF 5 ITEM 1(A) NAME OF ISSUER: VioQuest Pharmaceuticals, Inc. (the "Issuer") ITEM 1(B) ADDRESS OF THE ISSUER'S PRINCIPAL EXECUTIVE OFFICES: 7 Deer Park Drive, Suite E Princeton Corporate Plaza Monmouth Junction, NJ 08852 ITEM 2(A) NAME OF PERSON FILING: Lindsay A. Rosenwald, M.D. (the "Reporting Person"). ITEM 2(B) ADDRESS OF PRINCIPAL BUSINESS OFFICE OR, IF NONE, RESIDENCE: c/o Paramount BioCapital Investments, LLC 787 Seventh Avenue, 48th Floor New York, NY 10036 ITEM 2(C) CITIZENSHIP: The Reporting Person is a citizen of the United States. ITEM 2(D) TITLE OF CLASS OF SECURITIES: Common Stock (the "Shares"). ITEM 2(E) CUSIP NUMBER: 927625103 ITEM 3. IF THIS STATEMENT IS FILED PURSUANT TO RULE 13D-1(B), OR 13D-2(B) OR (C), CHECK WHETHER THE PERSON FILING IS A: This Item 3 is not applicable. ITEM 4. OWNERSHIP: ITEM 4(A) AMOUNT BENEFICIALLY OWNED: As of October 18, 2005, the Reporting Person beneficially owned 3,425,999 Shares, consisting of (i) 2,044,000 Shares held directly by the Reporting Person; (ii) warrants to purchase 989,169 Shares held directly by the Reporting Person; and (iii) 392,830 Shares held by Paramount Biocapital Investments, LLC, of which the Reporting Person is managing member. ITEM 4(B) PERCENT OF CLASS: See Item 11 of the cover page. PAGE 4 OF 5 ITEM 4(C) NUMBER OF SHARES AS TO WHICH SUCH PERSON HAS: (i) Sole power to vote or direct Please see Item 5 of the the vote: cover page. (ii) Shared power to vote or to Please see Item 6 of the direct the vote cover page. (iii) Sole power to dispose or to Please see Item 7 of the direct the disposition of cover page. (iv) Shared power to dispose or to Please see Item 8 of the direct the disposition of cover page. ITEM 5. OWNERSHIP OF FIVE PERCENT OR LESS OF A CLASS: This Item 5 is not applicable. ITEM 6. OWNERSHIP OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON: See Item 4 Above. ITEM 7. IDENTIFICATION AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING REPORTED ON BY THE PARENT HOLDING COMPANY: This Item 7 is not applicable. ITEM 8. IDENTIFICATION AND CLASSIFICATION OF MEMBERS OF THE GROUP: This Item 8 is not applicable. ITEM 9. NOTICE OF DISSOLUTION OF GROUP: This Item 9 is not applicable. ITEM 10. CERTIFICATION: By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having such purpose or effect. PAGE 5 OF 5 SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, the undersigned certifies that the information set forth in this statement is true, complete and correct. February 21, 2006 /s/Lindsay A. Rosenwald, M.D. ----------------------------- Lindsay A. Rosenwald, M.D.